Articles

Allium sativum (garlic) inhibits lipid synthesis by Candida albicans.

Author

Adetumbi M, Javor GT, Lau BH

Date

9/1986

Journal

Antimicrob Agents Chemother

Abstract

The effect of aqueous garlic extract on the macromolecular synthesis of Candida albicans was studied. Protein and nucleic acid syntheses were inhibited to the same extent as growth, but lipid synthesis was completely arrested. Blockage of lipid synthesis is likely an important component of the anticandidal activity of garlic.