Articles

Active oxygen species, articular inflammation and cartilage damage

Author

Henrotin Y

Date

1992

Journal

EXS

Abstract

Rheumatoid arthritis and osteoarthritis are age-related diseases, in which degenerative changes (arthrosis) and superimposed inflammatory reactions (arthritis) lead to progressive destruction of the joints. Active oxygen species derived from various sources play a role in this process, which may be influenced by appropriate treatment with antioxidants and free radical scavengers.