Articles

Isolation and hypoglycemic activity of quinquefolans A, B, and C, glycans of Panax quinquefolium roots.

Author

Oshima Y, Sato K, Hikino H

Date

3/1987

Journal

J Nat Prod

Abstract

An H2O extract of the American crude drug "Amerika-ninjin" (American ginseng), Panax quinquefolium roots, exhibited significant hypoglycemic activity in mice. Activity-guided fractionation of the extract led to isolation of three glycans, quinquefolans A, B, and C, which displayed hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.