Nutritional Composition And Potential Of Chempereia Manillana (BLUME) MERR As Herbal Medicine

Author

YUSMIZAWATI MOHD YUSOB

Date

2004

Keyword

ubat herba, Chempereia manillana (BLUME) MERR, tekanan darah, ujian antioksidan, ujian lethaliti , kandungan komposisi pemakanan , Sauropus androgynus , Ipomoea reptans, Piper sarmentosum , Centella asiatica

Abstract

Chempereia manillana (Blume) Merr is a fast growing woody plant species. Its young leaves are used as vegetables and 'ulam' by the Malays. This species is suspected not to be suitable for hypertensive subjects. It may cause severe headache. Not many studies have been done on the C. manillana except on its botanical aspects. The aim of this study is to evaluate the effect of C. manillana crude extracts on blood pressure, antioxidant activities, lethality test and proximate analysis. The result of proximate analysis of C. manillana is compared to Sauropus androgynus, Ipomoea reptans, Piper sarmentosum and Centella asiatica. In the first part of the study, young and old leaves were extracted using a range of polar to non polar solvents namely methanol, chloroform and hexane. Bioassay tests were conducted on the extract. The effect of the leaf extract was  tested  against the  blood  pressure,   lethality  of  brine  shrimp  and antioxidant. Proximate analysis included fiber and mineral. For in vivo test, ten rabbits were used. The result of proximate analysis showed that C. manillana (old leaves) contain high fiber (27.56%) when compared to the young leaves (15.21%). However, the carbohydrate content of the young leaves were 24.46% lower than the content of the old leaves (40.91%). The mineral content and the antioxidant value were very low. Lethality test showed that the crude extract was not toxic. Low blood pressure occur depending on the dosage and polarity of the solvent. The finding suggest that C. manillana extract is safe to be used with low dosage. The reduction of blood pressure was exponentially with the dose and reciprocal with time.