Sterols And Sterol Glycosides From Leaves Of Gynura aurantiaca DC

Author

A. Sadikun. A. Idrus and N. Ismail, School of Pharmaceutical Sciences, University Sains Malaysia 11800 Minden, Pulau Pinang.

Proceeding

Trends in Traditional Medicine Research, Proceedings of the International Conference on the Use of Traditional Medicine & Other Natural Products in Health Care

Date

8/6/1993

Keyword

Gynura aurantiaca; ß-sitosterol; stiginasterol; 3 ß -O- ß -D-glucopyranosylsitosterol;3 ß -0- ß -D-tetra-0-acetylglycopyranosylsitosterol.

Abstract

The petroleum ether extract of the leaves of Gynura aurantiaca on purification by silica gel column chromatography and TLC afforded a mixture of sterols containing ß -sitosterol and stigmasterol. From the chloroform extract, a mixture of steroid glycosides 3 ß -0-B-D-glucopyranosyl sitosterol (major) and 3 ß -0- ß -D-glucopyranosylstigmasterol (minor) was isolated. Acid hydrolysis of the glycosides gave the aglycone, a mixture of ß -sitosterol and stigmasterol which was identified by TLC and spectroscopic evidences. The sugar part was identified as D-glucose by TLC method. Acetylation of the glycosides with pyridine-acetic anhydride, 3 ß -0- ß -D-tetra-0-acetylglucopyranosylsitosterol was isolated and identified by IR, 1H and 13C NMR.