Phase 11 Clinical Trial On Effects Of Labisia pumila Water-Soluble Extract On Post Menopausal Women: Research Methodology

Author

1Nik Hazlina NH, 1Azidah AK ,1Wan Mohamad WB, 1Intan IH 1,2Wan Nazaimoon WM, 3Norlela S,3Nor Azmi K, 1School of Medical Sciences, Universiti Sains Malaysia, 2Institute for Medical Research, Kuala Lumpur, Malaysia, 3Faculty of Medicine, Universiti Kebangsaan Malaysia

Proceeding

1st International Conference & Exhibition on Women's Health & Asian Traditional (WHAT) Medicine

Date

23/8/2005

Keyword

women's health, Labisia pumila, Post menopausal women, herbal therapies

Abstract

One of the most important issues in women’s health concerns the risks and benefits of estrogen replacement therapy. However, continual uncertainty and lack of consensus of standard estrogen replacement therapy has driven many women to seek alternative sources of estrogen, including herbal remedies. Herbal therapies are popular alternatives to conventional therapies. In Malaysia, RM 2 billion is spent annually on herbal medicine. Despite the wide use of alternative medicine, little is known about the safety and efficacy of alternative treatments. While some herbs might be pharmacologically and clinically effective, they are not necessarily free of toxicity and side effects, nor can one be sure that they will not interact with prescription medications. Alternative medical therapies have attracted a great deal of attention from the media, medical community, governmental agencies, and the public. To date, there are no clinical studies looking at the effects of Labisia pumila on postmenopausal women. In view of the initial evidence that it is a phytoestrogen from animal studies and has androgenic properties as well, it should have a beneficial effect to these women in terms of improvement in their menopausal symptoms, changes in their endogenous hormonal profile, positive effects on the lipids and increase in bone mineral density.