image
Conservation

Compilation of herbal plants (description, geographical distribution, taxonomy, line drawings), biodiversity and herbarium.

Read More
image
Research & Publication

Description of herbal and T&CM research, searchable publication and process from medicinal plant discovery to clinical trial in producing a high-quality registered herbal drug.

Read More
 
Traditional & Complementary Medicine (T&CM)

 

Definition and description of therapies, policy, training and education, research in the practise of (T&CM) and integrated medicine system.           

Read More

 

News Update

Announcement & Advertisement

Forthcoming Events

14th International Conference on Biopharma and Biotherapeutics

From Fri, 25. October 2019 Until Sat, 26. October 2019

World Conference on Pharmaceutical Chemistry and Clinical Research

From Wed, 27. November 2019 Until Thu, 28. November 2019

15th Annual Congress on Pharmacology and Toxicology

From Mon, 2. December 2019 Until Tue, 3. December 2019

3rd International Conference and Exhibition on Pharmaceutical Nanotechnology and Nanomedicine

From Mon, 24. February 2020 Until Tue, 25. February 2020

21st Interntaional Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems

From Wed, 11. March 2020 Until Thu, 12. March 2020

Effects of apocynin, a drug isolated from the roots of Picrorhiza kurroa, on arachidonic acid metabolism.

Author

Engels F, Renirie BF, 't Hart BA

Date

6/7/1992

Journal

FEBS Lett

Abstract

Apocynin is a constituent of root extracts of the medicinal herb Picrorhiza kurroa and has been shown to possess anti-inflammatory properties. We investigated the effects of apocynin on the production of arachidonic acid-derived inflammatory mediators by guinea pig pulmonary macrophages. Apocynin concentration-dependently inhibited the formation of thromboxane A2, whereas the release of prostaglandins E2 and F2 alpha was stimulated. Apocynin potently inhibited arachidonic acid-induced aggregation of bovine platelets, possibly through inhibition of thromboxane formation. The present results suggest that apocynin might, beside its therapeutic effects in inflammatory conditions when given in a root extract of P. kurroa, also be a valuable tool in the development of new anti-inflammatory or anti-thrombic drugs.

Explore Further

Consumer Data

Consumer data including medicinal herbs, dietary supplement monographs, health condition monographs and interactions and depletions.                                    

Read More
Professional Data

Professional data organized into medicinal herbs, dietary supplement monographs, health condition monographs, T&CM herbs, formulas, health conditions, interactions and depletions.

Read More
International Data

We offer International linkages to provide extensive content pertaining to many facets of T&CM as well as Integrated Medicine. Please register for access.    

Read More