Articles

The effect of polyunsaturated fatty acids of the omega-3 class on the late phase of the allergic reaction in bronchial asthma patients

Author

Masuev KA

Date

1997

Journal

Ter Arkh

Abstract

Placebo-controlled study of changes in the course of atopic bronchial asthma (ABA) induced by supplement of the diet with polyunsaturated fatty acids of omega-3 class in 13 patients compared to placebo- treated subjects allowed the conclusion on significant attenuation of late allergic response in patients who had taken eiconol for two weeks. The effects of the acids are explained by a comparative replacement of arachidonic acid in the membranes of cell effectors of the inflammation with omega-3 fatty acids leading to inhibition of production of inflammation lipid mediators.