How Bifidobacteria interacts with Antibiotics

Interaction type: Depletions

Interaction rating: Proven

Bifidobacteria is part of the normal flora that resides in the colon and is susceptible to antibiotics. It is important to include bifidobacteria in probiotic supplementation following a course of antibiotics to facilitate repopulating the colonic environment with its primary beneficial bacteria. (1) (2)

These drugs include Aminoglycosides, Cephalosporins, Fluoroquinolones, Quinolones, Macrolides, Penicillins, Sulfonamides, Tetracyclines, Trimethoprin-containing antibiotics, Carbapenems, Monobactams, chloramphenicol, spectinomycin, Streptogramins, vancomycin, Oxalodinones, Lincosamides, Nitrofurans


  1. View Abstract: Lim KS, et al. Antimicrobial Susceptibility of Bifidobacteria. J Dairy Sci. Aug1993;76(8):2168-74.
  2. View Abstract: Charteris WP, et al. Antibiotic Susceptibility of Potentially Probiotic Bifidobacterium Isolates from the Human Gastrointestinal Tract. Lett Appl Microbiol. May1998;26(5):333-37.