Fu Ling

Poria, Hoelen

Dosage

9-15g.

Toxicity

One known potential adverse effect of poria is epispasis, a kind of allergic reaction. (1)

Chemical Composition

Pachymic acid; Tumulosic acid; Trametenolic acid; Eburicoic acid; Dehydroeburicoic acid; Poricoic acid; b-amyrin acetate; Pachyman; Pachymaran; Glucan H11; Ergosterol; Caprylic acid; Undecanoic acid; Lauroic acid; Dodecenoic acid; Palmitic acid; Dodecenoate; Caprylate; Fumulosic acid methylester; Polyporenic acid C methylester; Pachymic acid methylester; 7, 9 (11)-dehydropachymic acid; 7, 9 (11)-dehydropachymic acid methylester; 3b-hydroxy-lanosta-7, 9 (11), 24-trein-21-oic acid; 3b-hydroxy-16a-acetyloxylanosta-7, 9 (11), 24-trien-21-oic acid; 3b-,16a-dihydroxylanosta-7, 9 (11), 24 (31)-trien-21-oic acid methylester. (2) , (3) , (4) , (5) , (6) , (7) , (8) , (9)

Pharmacology

Anti-neoplastic effect

Pachman is an anticarcinogen. (10) Administering pachman to mice (5mg/kg) by abdominal injection daily for ten consecutive days inhibits S180 with a 95% inhibition rate. (11)

Enhancing immunity

Oral-feeding pachman to mice (250, 500, 1000mg/kg) daily for seven consecutive days enhances the phagocytic function of macrophage of both healthy and cancerous mice. (12)

Diuretic effect

Administering alcohol-based extract of this herb to rabbits at 0.5g/kg daily for five consecutive days shows a diuretic effect. (13) , (14)

Calming effect

Administered at the dosages of 5, 10, 20g/kg, the water decoction of fushen, a variation of this herb (with pine roots growing into it), counteracts the caffeine-induced excitation in mice. (15)

Protecting the liver

Injecting poria injection into hamsters at 1.4g/kg daily for eight consecutive days can counteract carbon tetrachloride-induced liver damage. (16)

Antibacterial

Experiments show that the 100% water decoction of this herb inhibits Staphylococcus aureus, Bacillus coli, and Bacillus proteus. (17)

References

  1. Liu Xue Ru, et al. China Journal of Hospital Pharmacy. 1992;12(8):379.
  2. Wang Li Wa, et al. Journal of Chinese Materia Medica. 1998;29(3):145-148.
  3. Li Yu Qi. Practical Journal of Combining TCM & Western Medicine. 1998;11(7):643.
  4. Pan Qi, et al. Journal of Yunnan College of TCM. 1998;21(4):20-21.
  5. Pan Qi, et al. Journal of Yunnan College of TCM. 1999;20(1):33-34.
  6. Wang Li Ya, et al. China Journal of Chinese Medicine. 1993;18(10):613.
  7. Guo Xin Fang, et al. Journal of Contemporary Chinese Medicine. 1993;4(1):15.
  8. Cai Chuan Ying, et al. Journal of Chinese Materia Medica. 1984;15(2):61.
  9. Lin Si Lan, et al. China Journal of Chinese Medicine. 1991;16(4):222.
  10. Zhou Mei Xiu. Fujian Journal of Medicine. 1982;4(4):back cover.
  11. Chen Chun Xia. Journal of Chinese Materia Medica. 1986;16(4):40.
  12. Lu Su Cheng, et al. Journal of No. 1 Military Academy. 1990;10(3):267.
  13. Lu Ding, et al. Journal of China Medical Academy. 1987;9(6):433.
  14. Lu Ding, et al. Journal of China Medical Academy. 1988;10(4):294.
  15. Hu Chong Jia. Journal of Wuhan Medical College. 1957;(1):125.
  16. Han De Wu, et al. China Journal of Internal Medicine. 1977;2(1):13.
  17. Nanjing College of Pharmacy. Materia Medica, vol. 2. Jiangsu: People's Press; 1976.