Bai Zi Ren

Biota Semen, Biota Seed

Dosage

Oral usage, decoction 10~15g. 5:1 concentrated extract: 2-3 grams/day.

Chemical Composition

Cedrol; Sitosterol; Diterpenes; Pinusolide; 15, 16-bisnor-l3-oxo-8(17)-labdene-19-oic acid; 15, 16-bisnor-l3-oxo-8(17), 11E-labdadien-19-oic acid; 14, 15, 16-trisnor-8(17)-labdene-l3, 19-dioic acid; 12R, 13RS-dihydroxycommunic acid; Methyl ester. (1) , (2)

Precautions

Those with loose stool and abundant expectoration use the herb with caution.

Pharmacology

Strengthening memory

Administered to mice with damaged basal nuclei of the forebrain, Bai Zi Ren can improve the subjects’ passive avoidance learning capacity. In experiments involving darkness avoidance and table-jumping activities, it is found that the daily administration of an alcohol-based extract of Bai Zi Ren (250mg/kg and 500mg/kg daily for 15 consecutive days) given to mice with basal nuclei damage of forebrain on both sides can ameliorate the subjects’ dysmnesia (impaired memory) and memory loss. (3)

References

  1. Editorial Committee of Chinese Materia Medica, State Drug Administration of China. Chinese Materia Medica. Shanghai Science and Technology Press, 1998.
  2. Li Shu Zhi, et al. The chemical composition of Bai Zi Ren oil. Journal of Chinese Patent Medicine. 1999;21(2):88-89.
  3. Chu Peng Jiang. Bai Zi Ren’s effect on passive avoidance learning in mice with damage in forebrain’s basal nuclei. Foreign Medicine,vol. of TCM. 1993;15(2):40.