Che Qian Zi

Plantaginis Semen, Plaintain Seed

Dosage

5-15g decoction, or take in pill or powder form.

Chemical Composition

Aucubin; Plantasan; D-xylose; D-galacturonic acid; L-rhamnose; D-galactose; L-arabinose; Succinic acid; Adenine; Choline; Plantagomuliliage A; Plantagoside; Geniposidic acid; Plantenolic acid; b-sitosterol; b-sitosteryl-3-O-b-D-glucopyranoside; Isoquercitrin; Vitamin B1, A. (1) , (2) , (3) , (4) , (5)

Inorganic Chemicals

Fe, Mn, Zn, Cu.

Precautions

Contraindications: Prolapse of yang-qi, emission due to kidney deficiency, non-interior dampness syndromes.

Pharmacology

Anti-inflammatory effects

Che Qian Zi can significantly decrease capillary permeability in the skin and in the abdominal cavity, and decrease red blood cell membrane’s permeability. (6) Experiments on the adherence of Neisseria gonorrheae to human urethra epithelial cells show that Che Qian Zi can significantly decrease the number of NG adhered to the surface of human urethra epithelial cells, and help keep the host organism relatively intact. (7)

Anti-aging effects

Experiments show that administered to mice, Che Qian Zi can significantly increase the activity of superoxide dismutase (SOD), decrease the lipid peroxide level, increase the median hemolytic concentration (HC50), lengthen the subjects’ swimming time, and enhance their anti-hypoxic capability. (8)

Effects on gastrointestinal movement

Che Qian Zi can increase the water content in the intestine, improve peristalsis and bowel movement, and relieves diarrhea. (9) Che Qian Zi gelatin, however, has a lapactic effect, and helps ameliorate constipation. (10)

Effects on the joint capsule

Experiments show that injected to rabbits’ knee cavity, 5% Che Qian Zi solution can promote the proliferation of join capsule synovium’s connective tissue, thereby recovering the normal tension of relaxed joint capsules. (11)

Effects on intraocular pressure

Experiments show that administered to rabbits by endogastric perfusion at 2.5g/kg for 3-6 days, Che Qian Zi can slightly lower the subjects’ intraocular pressure. The treatment can not counteract water load-induced increase in intraocular pressure in rabbits, however. (12)

References

  1. Guo Yue Qiu, et al. Determining the content of aucubin in Che Qian by HPLC. China Journal of Chinese Medicine. 1991;16(12):743-744.
  2. Zheng Tai Kun, et al. Advances in research on Chinese herb Che Qian. Liaoning Journal of Traditional Chinese Medicine. 1985;9(8):41-42.
  3. Liu Qi, et al. An analysis of trace elements in selected Chinese herbs. Journal of Changchun College of TCM. 1993;9(4):52.
  4. Shi Xiu Zhi, et al. An analysis of trace elements in Wu Zi Yan Zhong Wan and its constituent single herbs. Journal of Hebei Medical College. 1992;13(3):137-139.
  5. Editorial Committee of Chinese Materia Medica. State Drug Administration of China. Chinese Materia Medica. Shanghai: Science and Technology Press; 1998.
  6. Zhang Zhen Qiu, et al. Che Qian Zi pharmaceutical effects. Journal of Traditional Chinese Medicine Material. 1996;19(2):87-89.
  7. Wu Xi Guang, et al. The effects of eight Chinese herbs on the adhesion of Neisseria gonorrhoeae. China Journal of Dermatology. 1992;25(6):372-374.
  8. Zhang Zhen Qiu, et al. Che Qian Zi pharmaceutical effects. Journal of Traditional Chinese Medicine Material. 1996;19(2):87-89.
  9. Zhang Zhen Qiu, et al. Che Qian Zi pharmaceutical effects. Journal of Traditional Chinese Medicine Material. 1996;19(2):87-89.
  10. Zhang Zhen Qiu, et al. Che Qian Zi gelatin’s effect on constipation in mice. Journal of Shizhen Medicinal Material Research. 1996;7(4):209-210.
  11. John Chen, et al. Che Qian Zis effect on rabbits’ joint capsule. Traditional Chinese Medicine Bulletin. 1986;11(11):46-47.
  12. Li Wen Ming, et al. The effects of Si Zi Tang’s constituent herbs on rabbits’ intraocular pressure. Yunan Journal of TCM. 1990;11(4):27-28:36.