Long Yan Rou

Arillus Longan, Longan Aril

Dosage

Oral administration: 10 to 15g for decoction, up to 30 to 60g for large doses. The herb can also be made as extracts, infusion with alcohol, or made into pills and powder.
5:1 concentrated extract: 2 to 3g for decoction.

Toxicity

Mice were given a compound extract of Long Yan Rou (1g/ml) and Ge Jie (0.5g/ml), at 25ml/kg. Six hours later, the extract was given again. After 7 days of observation, no adverse reactions or deaths were found. (1)

Chemical Composition

Vitamin A, B1, B2, C, P (vitamin P is related to lemon); Glucose; Sucrose; Tartaric acid; Adenine; Lysophosphatidyl choline; Phosphatidyl choline; Phosphatidylinositol; Phosphatidylserine; Phosphatidyl-ethanolamine; Phosphatidic acid; Phosphatidyl glycerol; 2-amino-4-methylhex-5-ynoic acid; 2-amino-4-hydroxymethylhex-5-ynoic acid; 2-amino-4-hydroxyhept-6-ynoic acid; Dihydrosterculic acid; Quercetin; Quercitrin; Tannic acid; Friedlin; Epifriedelanol; b-sitosterol; Stigmasterol; Stigmasteryl-b-D-glucoside; Stigmasterol; Fucosterol. (2) , (3) , (4)

Precautions

Long Yan Rou should be used with caution in patients with phlegm-fire and retention of dampness in the chest. Decoctions with large quantities of Long Yan Rou can induce reactions such as dizziness. (5)

Pharmacology

Anti-cancer effect

A Long Yan Rou water extract can inhibit human cervical carcinoma cells, JTC-26, by more than 90% inhibition rate. (6)

Antibacterial effect

A Long Yan Rou water decoction (1:2) has inhibitory effects on sporular trichophytii and Bacillus dysenteriae. (7) Long Yan Rou leaf has antibacterial effects on B. subtillis. (8)

Anti-stress effect

A combination of Long Yan Rou (1g/ml) and Ge Jie (0.5g/ml) extracts, when administered via the stomach at 20ml/kg/dx10, had significant protective effects on mice suffering from irritation due to low temperature, high temperature, and hypoxia. It can also increase mouse body weight. When given by stomach at 15ml/kg/dx14, the combination can significantly antagonize a body weight decrease in mice. Administration through the stomach at 15ml/kg/dx10 can increase carbon removal in mice that were previously subject to intravenous injections of carbon granules. At 20ml/kg/dx7, it can increase mouse spleen weight. (9)

Others

Long Yan Rou can inhibit xanthoprotein MAO-B activity, which enhances human senescence. Its extract can selectively inhibit brain MAO-B activity, according to a model of MAO-B activity in isolated mouse brain and liver. (10)

References

  1. Nong Xing Xu, et al. Pharmacological effects of Gui Yuan Rou and Ge Jie. China Journal of Chinese Medicine. 1989;14(6):365-367.
  2. Chinese Materia Medica. Shanghai Science and Technology Press, 1998.
  3. Modern TCM Pharmacology. Tianjin Science Technology Translation Press, Inc. 1997.
  4. Li Li, et al. Analysis of Long Yan Rou phospholipid component. China Journal of Chinese Medicine. 1995;20(7):426.
  5. Zou Ying Fa. 2 reports of resistance due to weak constitution as areult of large dosage of Gui Yuan Rou Tang. Sichuan Journal of TCM. 1996;14(9):35.
  6. Chang Min Yi, et al. New theories on anti-aging activities of Long Yan Rou and He Shou Wu. Journal of Chinese Food. 1987;(2):4.
  7. Li Guang Xun. Journal of Pharmacology, Toxicity and Clinical Application of TCM. Tianjiang Science and Technology Translation Company. 1992: 371.
  8. Huang Tong Wang, et al. Selected research on 30 kinds of Chinese herbs’ antibacterial effects. Journal of New TCM. 1996;28(12):46-47.
  9. Nong Xing Xu, et al. Pharmacological effects of Gui Yuan Rou and Ge Jie. China Journal of Chinese Medicine. 1989;14(6):365-367.
  10. Chang Min Yi, et al. New theories on anti-aging activities of Long Yan Rou and He Shou Wu. Journal of Chinese Food. 1987;(2):4.