Antioxidant Activity and Effect of Oral Consumption of White Type Edible Jellyfish, Labonema smiithi

Author

ASSOC PROF DR MOHD EFFENDY ABD WAHID/ UNIVERSITI MALAYSIA TERENGGANU
1Suvik A.,  1Effendy A.W.M. and 1Habsah M.
1Institute of Marine Biotechnology

Language

English

Title

Antioxidant Activity and Effect of Oral Consumption of White Type Edible Jellyfish, Labonema smiithi on Wound Healing Process.

Proceeding

7th INTRACOM – 2nd ICBWI 2009

Date

24th July 2009

Place Held

PWTC, Kuala Lumpur

Abstract

The potential of edible jellyfish (Labonema smithii) as collagen stimulator in wound healing process was conducted. The study also determined the antioxidant activity of methanolic extract of the species, as well as its crude protein. The anti-oxidant activity was assayed at different concentrations ranging from 0.2 to 10 mg/ml by the 1, 1-dipheyl-2-picrylhrazyl (DPPH) free radical scavenging. Incised wounds at 8 mm in diameter were created on the dorsal area of control and treatment group of white rats. The treatment group was fed with freeze-dried jellyfish powder (1000 mg/kg) while the control group was fed with normal pellet daily. Physical observation and measurement of wound reduction was recorded daily for 21 days. The granulation tissues, kidney and liver were removed and blood was drawn from each rat on days 7, 14 and 21 post-wounding. The samples were then processed for histology, hematology and immunohistochemistry respectively. Antioxidant assay showed that the methanolic crude extract has higher antioxidant activity (46.78%) when compared with crude protein (37.60% ). Histologically, no side effects were noted on the liver and kidney in treatment rats, even at  high dose (2000mg/kg).  Epithelialization and wound reduction rate was significantly higher (p<0.05) in treatment animals. Full wound closure was completed at day 13 of post wounding compared to normal at day 17. Histological analysis confirmed that the epithelialization and reconstruction process was faster in the treatment group with high collagen deposition and intensity at day 21.  Hematological analysis showed that the white blood cell count was at normal range in both treatment and control group. These findings clearly substantiate the beneficial effects of jellyfish consumption in the accelerating the wound healing process

Keywords

Antioxidant Activity, Labonema smiithi, Edible jellyfish

Session

Symposium 2C (ICBWI)

Topic

Cosmeceutical/ Function/ Bioprocess