Chemical Constituents and Antimicrobial Activities of Goniothalamus Species

Author

Siti Humeirah A.G., Nor Azah M.A., Puad A., Muhajir H., Mastura M., Mailina J., Abu Said A., Mohd Faridz Z.P., Nik Yasmin N.Y. & Ahmad Abdul Qayyum M.
Medicinal Plants Programme, Forest Biotechnology Division, Forest Research Institute Malaysia, 52109 Kepong, Selangor
Institute of Bioscience, Universiti Putra Malaysia. Serdang 434O0 Selangor
Tel: 03-62797362 Fax: 03-62729805 Email This email address is being protected from spambots. You need JavaScript enabled to view it.

Language

English

Title

Chemical Constituents and Antimicrobial Activities of Goniothalamus Species

Proceeding

Medicinal and Aromatic Plants Seminar (MAPS 2008)

Date

42nd October - 22nd October 2008

Place Held

The Legend Hotel, Kuala Lumpur

Abstract

The aerial parts of Goniothalamus macrophyllus and G. tortilipetalum were collected from the Pasoh Forest Reserve and subjected to hydro-distillation for 8 h. Essential oils obtained were analyzed by GC and GC/MS analytical methods. The results showed that the oils possessed several major compounds. The twigs of G. macrophyllus contained geranyl acetate (45.5%), linalool (12.7%) and geraniol (17.0%) and the root contained cyperene (9.8%). geranyl acetate (9.4%) and camphene (7.5%). The leaves of G. tortllipetalum contained 0-cymene (43.0%), piperitone (11.5%) and 1,8-cineole (5.8 %). Antimicrobial activities of all the oils were evaluated against 11 micro-organisms including Multidrug Resistant Staphylococcus aureus (MRSA). gram-positive bacteria, gram-negative bacteria and dermatophytic fungi using single concentration test and broth micro-dilution method. All the oils inhibited the growth of the test micro-organisms studied except Pseudomonas aeruginosa (a gram-negative bacterium). The gram- positive bacteria were more sensitive to the extracts than the gram-negative bacteria and fungus. The antimicrobial activity could be due to the presence of geraniol and linalool which have been reported to have significant activities.

Keywords

Goniothalamus macrophyllus; Goniothalamus tortilipetalum; essential oil composition; antimicrobial activities

Session

Poster Abstracts

Topic

Think Global, Act Local: A New Paradigm In Malaysian Herbal Industry (Prof. Emeritus Dr. Abdul Latif Ibrahim-UNISEL)