Albizia myriophylla

Synonyms

Albizia microphylla, Albizia myriophylla, Albezia thorelli, Albizia vialeana, Mimosa microphylla.

Vernacular Names:

Malaysia Tebu Gajah
Thailand
Cha Aem Thai
Laos
Kheua Han Khao
India
Tetooleeya

General Information

Description

Albizia myriophylla is a member of the Fabaceae family. It is a small tree that could reach a height of 4m. The young shoots are dark brown in colour and scarcely villous. The leaves are bipinnate, from 15 to 20cm long, of bright green colour. The pinnae consist of 10 to 15 pairs. The leaflets are from 30 to 40 pairs, minute, obliquely-linear in shape and smooth. The petioles are common and partial, downy. The panicles are terminal and axillary, villous, composed of globular heads of minute greenish-yellow corollets. The bracts are subulate, villous with calyx and corolla both villous. The filaments are from 10 – 20, monodelphous. The germ is long-pediculed. The legumes are thin, leafy, smooth, long, broad and obtuse-pointed, from 3 to 6-seeded measuring 15-20cm long and rather above one broad. The seeds are oval, flat, smooth in shape and light brown in colour.[6]

Plant Part Used

No documentation

Chemical Constituents

1-deoxymannojirimycin (DMJ); 2-O-beta-D-glucopyranosyl-DMJ; 4-O-beta-D-glucopyranosyl-DMJ;   albiziasaponins A-E;  licorice-saponin F3; yunganoside B;  gallic acid, gentisic acid, p-hydroxybenzoic acid, vanillic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid, salicylic acid, quercetin, eugenol and kaempferol.[4] [5] [7]

Traditional Used:

In Laos the plant is used to treat gonorrhoea.[1]

In Thailand it is a remedy for cough.

Pre-Clinical Data

Pharmacology

Antifungal activity

Screening [2] of 23 Thai medicinal plants for their anticanddial activity against six Candida species i.e. Candida albicans, Candida glabarata, Candida guilliermondii, Candida parapsilosis and Candida tropicalis. The extract of A. myriophylla was found to have the broadest anticandidal activity against all Candida species. The MIC to all Candida species ranged from 100 – 500mg/ml with a fast acting killing activity and the reduction in the number of CFU/ml was >3 log(10_ unites (99.9%) in 2 hours.

Toxicities

No documentation

Clinical Data

Clinical Trials

Amorchat et al [3] did a clinical study on the effectiveness of A. myriophylla mouth wash on mutan streptococci and immunoglobulin A levels in saliva of 67 school children. They found that in the group of children who did a twice daily mouth rinsing activity for two weeks, there was a significant reduction of MS counts but not the IgA level.

Adverse Effects in Human:

No documentation

Used in Certain Conditions

Pregnancy / Breastfeeding

No documentation

Age Limitations

Neonates / Adolescents

No documentation

Geriatrics

No documentation

Chronic Disease Conditions

No documentation

Interactions

Interactions with drugs

No documentation

Interactions with Other Herbs / Herbal Constituents

No documentation

Contraindications

Contraindications

No documentation

Case Reports

No documentation

References

  1. Asia Pacific Medicinal Plant Database. http://219.93.41.233/wapi/mctweb.dll/getObject?MID=MEDICINALPLANT&ObjID=5328 [Accessed on 11th December 2010]
  2. Rukayadi Y, Shim JS, Hwang JK. Screening of Thai medicinal plants for anticandidal activity. Mycoses. 2008 Jul;51(4):308-12. Epub 2008 Mar 4.
  3. Amornchat C, Kraivaphan P, Dhanabhumi C, Tandhachoon K, Trirattana T, Choonhareongdej S. Effect of Cha-em Thai mouthwash on salivary levels of mutans streptococci and total IgA. Southeast Asian J Trop Med Public Health. 2006 May;37(3):528-31.
  4. Asano N, Yamauchi T, Kagamifuchi K, Shimizu N, Takahashi S, Takatsuka H, Ikeda K, Kizu H, Chuakul W, Kettawan A, Okamoto T. Iminosugar-producing Thai medicinal plants. J Nat Prod. 2005 Aug;68(8):1238-42.
  5. Yoshikawa M, Morikawa T, Nakano K, Pongpiriyadacha Y, Murakami T, Matsuda H. Characterization of new sweet triterpene saponins from Albizia myriophylla. J Nat Prod. 2002 Nov;65(11):1638-42
  6. William Roxburgh Flora Indica or Description of Indian Plants W. Thacker and Co. Calcutta 1832 pg. 549 – 550
  7. PANMEI Chamgongliu; SINGH P. K.; GAUTAM Satyendra; VARIYAR Prasad S.; SHANTIBALA DEVI G. A.; SHARMA Arun Phenolic acids in Albizia bark used as a starter for rice fermentation in Zou preparation International journal of food, agriculture and environment  2007, vol. 5(3-4):147-150
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