Study on Senna alata and its Different Extracts by Fourier Transform Infrared Spectroscopy (FT-IR) and Two-Dimensional Correlation Infrared Spectroscopy (2D-IR)

Author

Adiana M.A. and Mazura, M.P. Medicinal Plants Division, Forest Research Institute Malaysia, 52109, Kepong, Selangor. 
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Language

English

Title

Study on Senna alata and its Different Extracts by Fourier Transform Infrared Spectroscopy (FT-IR) and Two-Dimensional Correlation Infrared Spectroscopy (2D-IR)

Proceeding

Medicinal and Aromatic Plants Seminar (MAPS 2010)

Date

3rd August - 4th August (2010)

Place Held

Forest Research Institute Malaysia(FRIM)

Abstract

Senna alata L. locally known as gelenggang besar belongs to the family Fabaceae. It is widely distributed in the tropical countries, stretching from America to India, Fiji, Indonesia and Malaysia. It is commonly known as candle bush, with reference to the shape of its inflorescence, or ringworm tree because of its traditional use. The plant has been reported to possess anti- inflammatory, analgesic, laxative and anti-platelet aggregating activity. In Malaysia, especially among the traditional medicinal practitioners the S. alata leaves are also used to treat ringworm infection. In this study, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional infrared correlation spectroscopy (2D-lR) to study the main constituents of S. alata and its different extracts (extracted by hexane, dichloromethane, ethyl acetate and methanol). The findings indicated that FT-IR and 2D-IR could provide many holistic variation rules of chemical constituents. Use of the macroscopic fingerprint characters of FT-IR and 2D-IR spectrum could identify the main chemical constituents in medicinal plant materials and their extracts, but also compare the component differences among similar samples. This analytical method is highly rapid, effective, visual and accurate for medicinal plants research.

Keywords

Senna alata; Fourier Transform Infrared (FT-IR); two-dimensional infra red correlation spectroscopy (2D-IR); second derivative infrared spectroscopy; macroscopic fingerprint

Session

Poster Abstracts: P44

Topic

Harnessing the Tropical heritage: Recent Advances in R&D and commercialization