Home > Research Publications > Publications > Capsaicin-sensitive mechanisms and experimentally induced duodenal ulcers in rats.

Capsaicin-sensitive mechanisms and experimentally induced duodenal ulcers in rats.

Author

Maggi CA, Evangelista S, Abelli L

Date

7/1987

Journal

J Pharm Pharmacol

Abstract

The incidence and degree of cysteamine- or dulcerozine-induced duodenal ulcers are increased by systemic capsaicin desensitization (50 mg kg-1 s.c. 4 days before) in adult rats. Acute administration of capsaicin, but not neurokinins or CGRP, produced a small but distinct plasma extravasation (Evans blue leakage) in the rat proximal duodenum which was absent in capsaicin-pretreated rats. These findings indicate the existence of a capsaicin-sensitive ‘duodenal defence mechanism’ in rats.

in this scope

Research

Research In Herbal
Research in T&CM Medicine (Currently Not Available)

Publications

QUICK LINKS

Contact Information

GlobinMed Secretariat,
Integrative Health Information Unit
(Unit Informasi Kesihatan Integratif),

Herbal Medicine Research Center,

Institute for Medical Research,

Block C, National Institutes of Health (NIH),

No.1, Jalan Setia Murni u13/52,

Seksyen U13, Bandar Setia Alam,

40170 Shah Alam, Selangor

Tel: +603-33627657
Email: [email protected]

Disclaimer

The Government of Malaysia and Institute for Medical Research (IMR) shall not be liable for any loss or damage caused by the usage of any information obtained from this web site.