Author
Hanauer SB, Baert F
Date
1994
Journal
Med Clin North Am
Abstract
Despite advances in pharmacologic approaches, the treatment of ulcerative colitis and Crohn’s disease remains a challenge. Prior standards of therapy, sulfasalazine and corticosteroids, are gradually being replaced by mesalamine and alternative immune modulating agents. This article discusses the important pharmacologic properties, mechanisms of action, indications, and complications necessary to apply the expanding armamentarium in clinical practice.