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Kaempferia angustifolia Roscoe

Synonyms

Kaempferia undulata Link, Kaempferia roxburghiana Schult., Kaempferia augustifolia Roxb. [6]

Vernacular Names

Malaysia Cekur jantan
China Ciok Yek San Nai [1]
Indonesia Kunci pepet (Java); Kunci kunir (sunda); Kance pet (Madura) [1]
India Kanjan-bura [2]

General Information

Description

Kaempferia aungustifolia is a member of the Zingiberaceae family. The leaves are radical, linear-lanceolate and wavy. The spikes are hidden in the centre of the leaves. The upper two segments of the inner border of the corolla are linear, oblong, obtuse. [3]

Plant Part Used

Rhizome, flowers [1]

Chemical Constituents

2'-hydroxy-4, 4', 6'-trimethoxychalcone; 6-methylzeylenol; (24S)-24-methyl-5α-lanosta-9(11),25-dien-3β-ol;β-sitosterol; β-sitosterol-3-O-β-D-glucopyranoside; angustifolienol; benzoic acid; benzo[g]isoquinoline-5,Iodione; boesenboxide; crotepoxide;  hexadecanoic acid; kaempfolienol; p-sitosterol; sucrose; stigmasterol; tetracosanoic acid; ursolic acid; zeylenol. [4] [5]

Traditional Uses

The rhizome of K. aungustifolia is traditionally used to treat diarrhoea, bleeding disorder, abscesses, obesity problem, coughs, and to aid chewing process. [1][5] While the whole is a remedy for colds, stomach ache and intestinal infections. [5]

Pre-Clinical Data

Pharmacology

Cytotoxic activity

Crude extracts of K. angustifolia did not show any cytotoxic activity. However, pure compounds isolated from K. angustifolia such as augustifolienol and crotepoxide showed strong activity. [4] Kaempfolienol and zeylenol isolated from K. angustifolia was active against HL-60, MCF-7, HT-29 and HeLa cell lines. [5]

Antimicrobial activity

The crude extract of K. angustifolia and its isolated compound boesenboxide extract were found to be active towards some of the microbes when exposed to MRSA, Pseudomonas aeruginosa, Salmonella typhimurium and Bacillus subtilis.  [4]

Antioxidant activity

Some of the compounds from K. angustifolia were found to exhibit antioxidant activity stronger than a-tocopherol. [4]

Toxicities

No documentation

Teratogenic effects

No documentation

Clinical Data

Clinical Trials

No documentation

Adverse Effects in Human:

It is contraindicate during pregnancy. [1]

Used in Certain Conditions

Pregnancy / Breastfeeding

No documentation

Age Limitations

Neonates / Adolescents

No documentation

Geriatrics

No documentation


Chronic Disease Conditions

No documentation

Interactions

Interactions with drugs

No documentation

Interactions with Other Herbs / Herbal Constituents

No documentation

Contraindications

Contraindications

No documentation

Case Reports

No documentation

References

  1. Hariana HA. Tumbuhan Obat dan Khasiatnya Volume 2, Niaga Swadaya, Jakarta 2008, pg. 67 – 68
  2. Nadkharni KM, Dr. KM. Nadkarni’s Indian Materia Medica Volume 1 Popular Prakashan, New Delhi 1996, pg. 715
  3. Roxburgh W. Wallich N. Flora Indica Volume 1, Mission Press, Serampore 1820, pg. 16
  4. Neoh, Bee Keat. Chemical Constituents and Biological Activity of Kaempferia angustifolia, K. rotunda,Spermacoce articularis and S. exilis. PhD thesis. 2006. Universiti Putra Malaysia.
  5. Tang SW, Sukari MA, Rahmani M, Lajis NH, Ali AM. New abietene diterpene and other constituents from Kaempferia angustifolia Rosc. Molecules. 2011 Apr 7;16(4):3018-28.
  6. The Plant List. Available from http://www.theplantlist.org/tpl1.1/record/kew-250750 Accessed on 24th June 2014

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