High Alpha-bisabolol Oxides Content Volatile Oil of Isfahanian Chamomile


Alireza Ghannadi, Mohammadreza Shams-Ardakani and Azadeh Rahimzadeh


Traditional & Complementary Medicine Exhibition 2007 (TCME 2007), Putra World Trade Centre (PWTC), Kuala Lumpur, Malaysia




chamomile, volatile oil, bisabolol oxides


Chamomile is one of the most important medicinal plants of Iran that belongs to the Asteraceae family. It has distributed in some regions of Iran. The Iranian flora comprises 2 species of chamomile and one of them isMatricaria recutitaL. This plant has been added to a variety of foods, cosmetics and remedies for flavoring and its pharmacologic effects. It is extensively used for treating of some gastrointestinal and rheumatic diseases. There are several reports on the composition of the volatile oil ofM. recutita. Literature survey revealed that the volatile oil of cultivatedM. recutitain Isfahan has not been chemically studied to date, therefore the present paper deals with the oil analysis by GC and GC/MS. In this research theM. recutitaaerial parts were obtained from the campus of Isfahan University of Medical Sciences in spring 2001. The volatile fraction was isolated by hydrodistillation according to the British Pharmacopoeia method. GC and GC-MS analyses on the Isfahanian chamomile volatile oil were carried out. The identification of the oil constituents was based on MS literature data, computer library searches and retention indices with those of authentic compounds. Our finding showed that most of the total components were identified in the oil. Alpha-and beta-bisabolol oxides (ca. 40 %) were the major constituents of the oil. Isfahanian chamomile produces a volatile oil which is different from those known chamomile oil sand this will be a valuable source of bisabolol oxides.