Effect of daily calcium supplementation on the incidence of hypertensive disorders of pregnancy: a study protocol


Rama Dev


1st National Symposium On Clinical Nutrition, Kuala Lumpur, Malaysia.




calcium supplementation, hypertensive disorders, pregnancy


Hypertensive disorders of pregnancy encompass a wide spectrum of disorders ranging from asymptomatic elevated blood pressure to life-threatening eclampsia. An observation of the labour room records at the Maternity Hospital, Kuala Lumpur showed that of approximately 2000 deliveries conducted each month, about 5% are associated with varying degrees of severity of this problem. The consequences of hypertension in pregnancy include multiple antenatal admissions, prolonged post-natal stay in hospital, use of expensive non-teratogenic drugs, repeated laboratory tests, prolonged CTG monitoring and of course increased maternal and foetal morbidity and mortality to name a few. Some studies done in America, Argentina and Equador suggest a significant decrease in incidence of this problem when 1 or 2 grams of elemental calcium is given from about the twentieth week of pregnancy until delivery. This paper presents the protocol of a proposed study to be conducted in the Maternity Hospital Kuala Lumpur, to determine if the implementation of calcium supplementation in pregnancy will significantly reduce the incidence of hypertensive disorders of pregnancy.