Vitamin K Acupuncture Point Injection For Severe Primary Dysmenorrhoea: An International Pilot Study


Li Wang1 Francesco Cardini2 Wenjie Zhao1 Anna Laura Regalia3 Christine Wade Emanuela ForcellaJin Yu1, 1Obstetrics & Gynecology Hospital, Fudan University, Shanghai, P. R. China, 2 Istituto Superiore di Sanit , Roma, Italy, 3 Obs & Gyn Department, Hospital S. Gerardo (Monza), Milano Bicocca University, Italy, 4The Richard and Hinda Rosenthal Center for Complementary and Alternative Medicine, Columbia University


1st International Conference & Exhibition on Women's Health & Asian Traditional (WHAT) Medicine




Vitamin K acupuncture point injection, dysmenorrhoea, menstrual pain treatment , Traditional Chinese Medicine


Context: Vitamin K acupuncture point injection, a menstrual pain treatment derived from Traditional Chinese Medicine, has been a standard treatment in some hospitals in China since 1980’s. Objectives: to investigate the effects of Vitamin K acupuncture point injection on menstrual pain in young women ages 14-25 from different countries and cultural backgrounds who have had unmitigated menstrual pain for 6 months or more. Design: prospective observational clinical pilot study. Settings: one site in China (a hospital outpatient clinic in Shanghai), and two sites in Italy (a hospital clinic in Milan and a private gynecology practice in Verona). Interventions: all subjects were treated with bi-lateral acupuncture point injection of Vitamin K on the 1st or 2nd day of menstrual pain. Vitamin K3 was used in China and Vitamin K4 in Italy. Main Outcome Measures: pain intensity, total duration and average intensity of menstrual distress, hours in bed, normal daily activity restrictions and numbers of analgesic tablets due to pain were recorded before the treatment and for the following four menstrual cycles. Results: Noticeable pain relief was observed 2 minutes after treatment, and subsequent pain reduction occurred at 30 minutes (p<.001). Subjects reported significantly fewer daily life restrictions, hours in bed, consumption of analgesic tablets, and lower scores of menstrual pain duration and intensity (p<.001). There were no adverse events. Some women experienced mild self-limited pain at the injection site. Conclusion: Acupuncture point injection with Vitamin K alleviated acute menstrual pain, and relief extended through the non-treatment follow-up cycles in this uncontrolled pilot study conducted in two countries. Further investigation employing controlled experimental designs is warranted.