6-Month Double-blind Randomised Clinical Trial of Ginkgo biloba Extract Versus Placebo in Two Parallel Groups in Patients Suffering from Peripheral Arterial Insufficiency.


Bauer U




Arzneim-Forsch/Drug Res


79 patients suffering from peripheral arteriopathy (Fontaine's stage IIb) completed a 6-month double-blind randomised clinical trial of Ginkgo biloba extract (GBE) (as coated tablets containing 40 mg GBE; rokan) versus placebo in two parallel groups. From the results of measurements of pain-free walking distance, maximum walking distance and plethysmography recordings, GBE was shown to be active and significantly superior to placebo. These results correlated with the physician's and patients' overall assessment of response to treatment.