Intensity of free radical process and antioxidant enzymes activity in human saliva and plasma under emotional stress


Lukash AI




Vopr Med Khim


The intensity of free radical processes (FRP) and the activity of antioxidant (AO) systems in human blood plasma and saliva were studied under physiological emotional strain and depressive pathologies (before and after treatment). The significant alterations in the dynamics of investigative indexes under different emotional strain were revealed. These alterations in saliva were more intensive than in blood plasma. The treatment led to the stabilization of FRP intensity and the activity of AO protection. The correlation between saliva and blood plasma parametres allows to use saliva for the estimation of emotional strain and of the efficiency of therapeutics under depressive pathologies.