[Treatment with dimethylaminoethanol (deanol) in neuroleptic induced tardive dyskinesia].


Kocher R, Hobi V, Linder M, Studer K




Schweiz Arch Neurol Neurochir Psychiatr


A double blind cross-over study of 20 patients wiht tardive dyskinesia due to chronic use of neuroleptics showed no difference between efficacity of Deanol (Deaner) and placebo. Several patients improved with Deanol (Deaner), whereas several other patients showed increasing dyskinesia. The same phenomenon could be observed in the placebo group. Tolerance of the compound was very good. Results of an additional open study however suggest that the administration of Deanol (Deaner) may be tried as long as no other means are available to define those patients who will react favorably to this medication.