image
Conservation

Compilation of herbal plants (description, geographical distribution, taxonomy, line drawings), biodiversity and herbarium.

Read More
image
Research & Publication

Description of herbal and T&CM research, searchable publication and process from medicinal plant discovery to clinical trial in producing a high-quality registered herbal drug.

Read More
 
Traditional & Complementary Medicine (T&CM)

 

Definition and description of therapies, policy, training and education, research in the practise of (T&CM) and integrated medicine system.           

Read More

 

News Update

Announcement & Advertisement

Forthcoming Events

International Conference on Biotechnology and Healthcare

From Mon, 7. December 2020 Until Tue, 8. December 2020

International Conference on Malay Medical Manuscript

From Tue, 15. December 2020 Until Wed, 16. December 2020

International Conference on Natural Medicine and Nutrition (ICNMN) 2020

From Thu, 17. December 2020 Until Fri, 18. December 2020

1st Global Summit on Generic Drugs and Quality Control

From Fri, 22. January 2021 Until Sat, 23. January 2021

International Conference on Natural Products and Drug Discovery (ICNPDD) 2021

From Thu, 11. February 2021 Until Fri, 12. February 2021

The effect of magnesium on coagulation in parturients with preeclampsia

Author

Harnett MJ, Datta S, Bhavani-Shankar K

Date

5/1998

Journal

Anesth Analg

Abstract

Preeclampsia is associated with complex coagulation abnormalities that include altered platelet function and consumption and activation of the fibrinolytic system. Magnesium sulfate, which is used as a therapeutic modality for the prevention of seizures in preeclamptic parturients, has anticoagulant and antiplatelet effects. We sought to determine the effects of magnesium on various components of the coagulation system in patients with preeclampsia. We assessed the coagulation status of 18 parturients with preeclampsia being treated with magnesium. The assessment was performed with the thromboelastograph test, which provides an overall assessment of blood coagulation via the coagulation index. Thromboelastography was performed before beginning magnesium therapy and 30 min and 2 h after a 6-g bolus of IV magnesium. The R value (time to first clot formation) was found to be significantly slower (P < 0.05) at 30 min after the magnesium bolus. This result suggests increased coagulant factor activity resulting from the magnesium bolus. However, there was no effect of magnesium on the overall coagulation, as evidenced by the lack of change in the coagulation index either at 30 min or at 2 h after the completion of the initial magnesium bolus. Therefore, this therapy should have no effect on the use of neuraxial techniques. IMPLICATIONS: On the basis of the thromboelastography assessment, we found that the current practice of administering magnesium did not influence overall coagulation in preeclamptic women. Therefore, magnesium administration should not affect the use of neuraxial techniques.

Explore Further

Consumer Data

Consumer data including medicinal herbs, dietary supplement monographs, health condition monographs and interactions and depletions.                                    

Read More
Professional Data

Professional data organized into medicinal herbs, dietary supplement monographs, health condition monographs, T&CM herbs, formulas, health conditions, interactions and depletions.

Read More
International Data

We offer International linkages to provide extensive content pertaining to many facets of T&CM as well as Integrated Medicine. Please register for access.    

Read More