Nutrient intakes; biochemical and risk indices associated with Type 2 diabetes and glycosylated haemoglobin, in the British National Diet and Nutrition Survey of people aged 65 years and over.


Bates CJ, Lean ME, Mansoor MA, Prentice A.




Diabet Med


Abstract Aims To characterize nutritional differences between survey participants diagnosed with Type 2 diabetes; those without diabetes, and those with 'undiagnosed diabetes' based on glycosylated haemoglobin (HbA(1c)). Subjects and methods The 1994/5 British National Diet and Nutrition Survey, of people aged 65 years and over (mean age 78 years), included 73 respondents with diagnosed Type 2 diabetes [mean (sd) HbA(1c) = 7.06 (2.05)%], and 30 with 'undiagnosed diabetes' (defined as HbA(1c) > 6.3%; mean (sd) HbA(1c) = 7.40 (1.66)%], among a representative sample of 1038 with anthopometry; 4-day weighed diet; blood and urine status measurements. Results The prevalence of Type 2 diabetes (diagnosed + undiagnosed) was 10%. In subjects without diagnosis of diabetes, those with HbA(1c) > 6.3% had on average a significantly higher body weight (73.6 vs. 67.9 kg), higher waist circumference (99.8 vs. 91.8 cm), higher body mass index (28.6 vs. 25.9 kg/m(2)) and higher white cell counts (7.64 vs. 7.09 x 10(9)/l), than those with mean HbA(1c) 6.3%) were nutritionally 'at risk', having low plasma concentrations of lycopene (0.13 vs. 0.24 micro mol/l) and high density lipoprotein cholesterol (0.99 vs. 1.27 micro mol/l) and a trend towards low vitamin C (24 vs. 36 micro mol/l) which was significant (P < 0.01) for men. HbA(1c) was positively correlated with white cell count, plasma fasting triglycerides, plasma alkaline phosphatase and homocysteine (all P < 0.01 overall), being particularly striking amongst men. Conclusions Among older British citizens, those with diagnosed diabetes had healthier nutritional profiles than those undiagnosed with high HbA(1c). Important health-promoting benefits are therefore predicted following early diagnosis and nutritional advice for people with Type 2 diabetes. Diabet. Med. (2004)