How Cayenne interacts with Salicylates

Interaction type: Interactions

Interaction rating: Study Supported

An animal study reported that cayenne decreased the amount of aspirin absorped which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1)

These drugs include aspirin, choline salicylate, sodium salicylate, magnesium salicylate, salsalate, diflunisal, sodium thiosalicylate


  1. View Abstract: Cruz L, et al. Ingestion of Chili Pepper (Capsicum annuum) Reduces Salicylate Bioavailability After Oral Aspirin Administration in the Rat. Can J Physiol Pharmacol. Jun1999;77(6):441-46.