How Echinacea interacts with Immunosuppressive medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies have reported that echinacea stimulates our immune system, which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1) (2)

These drugs include azathioprine, basiliximab, cyclosporine, daclizumab, glatiramer, muromonab-cd3, mycophenolate mofetil, tacrolimus (FK506), sirolimus, methotrexate, prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone


  1. View Abstract: Vomel VT. The Effect of a Nonspecific Immunostimulant on the Phagocytosis of Erythrocytes and Ink by the Reticulohistiocyte System in the Isolated, Perfused Liver of Rats of Various Ages. Arzneim Forsch/Drug Res. 1984;34:691-95.
  2. View Abstract: See DM, et al. In Vitro Effects of Echinacea and Ginseng on Natural Killer and Antibody-dependent Cell Cytotoxicity in Healthy Subjects and Chronic Fatigue Syndrome or Acquired Immunodeficiency Syndrome Patients. Immunopharmacology. 1997;35(3):229-35.