How Garcinia interacts with Diabetic / Hypoglycemic medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Animal studies have reported that garcinia has the ability to lower blood sugar, which may alter the effects of these medications and possible the dose needed for treatment. Use with caution. (1) (2)

These drugs include Insulin, glyburide, glipizide, metformin, rosiglitazone, pioglitazone, glimepiride, tolbutamide, tolazamide, acarbose, acetohexamide, chlorpropamide, miglitol, repaglinide, nateglinide


  1. Lowenstein JM, et al. Effect of (-)-Hydroxycitrate on Fatty Acid Synthesis by Rat Liver in Vivo. J Biol Chem. 1971;246:629-32.
  2. Sullivan AC, et al. Inhibition of Lipogenesis in Rat Liver by (-)-hydroxycitrate. Arch Biochem Biophys. 1972;150(1):183-90.