How Guggul interacts with Antihyperlipidemic medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies have reported that guggul lowers both cholesterol and triglyceride levels. This may change the effect and possibly the dose of these medications. (1) (2) (3)

These drugs include atorvastatin, fluvastatin, lovastatin, pravastatin, simvastatin, cholestyramine, colestipol, colesevelam, gemfibrozil, fenofibrate, clofibrate, niacin (nicotinic acid)


  1. Satyavati GV, et al. Experimental Studies on the Hypocholesterolemic Effect of Commiphora Mukul. Indian J Med Res. 1969;57(10):1950-62.
  2. View Abstract: Nityanand S, et al. Clinical Trials with Gugulipid. A New Hypolipidaemic Agent. J Assoc Physicians India. 1989;37(5):323-28.
  3. Satyavati GV, et al. Guggulipid: A Promising Hypolipidemic Agent from Gum Guggul (Commiphora Wightii). Econ Med Plant Res. 1991;5:48-82.