How Guggul interacts with Thyroid medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies have reported that guggul stimulates the thyroid. This may change the effects and possibly the dose of these medications. Use with caution. (1) (2)

These drugs include thyroid desiccated, levothyroxine sodium, liothyronine sodium, liotrix, iodine products


  1. Tripathi YB, et al. Thyroid Stimulatory Action of (Z)-Guggulsterone: Mechanism of Action. Planta Med. 1988;54(4):271-77.
  2. View Abstract: Panda S, Kar A. Gugulu (Commiphora mukul) induces triiodothyronine production: possible involvement of lipid peroxidation. Life Sci. 1999;65(12):PL137-41.