How Shiitake Mushroom interacts with Immunosuppressive medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies have reported that shiitake mushroom stimulates our immune system, which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1) (2)

These drugs include azathioprine, basiliximab, cyclosporine, daclizumab, glatiramer, muromonab-cd3, mycophenolate mofetil, tacrolimus (FK506), sirolimus, methotrexate, prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone

References

  1. Suzuki H, et al. Immunopotentiating Substances in Lentinus edodes Mycelial Extract(LEM)-- Activation of Macrophage and Proliferation of Bone Marrow Cell. Nippon Shokakibyo Gakkai Zasshi. Jul1988;85(7): 1430.
  2. View Abstract: Suzuki H, et al. Inhibition of the Infectivity and Cytopathic Effect of Human Immunodeficiency Virus by Water-soluble Lignin in an Extract of the Culture Medium of Lentinus edodes Mycelia (LEM). Biochem Biophys Res Commun. Apr1989;160(1):367-73.