How Iron interacts with Salicylates

Interaction type: Depletions

Interaction rating: Study Supported

These medications can cause irritation and bleeding in the digestive tract. Depending on the amount of blood lost, iron depletion may result. Supplementation with affected nutrient may be necessary. (1)

These drugs include aspirin, choline salicylate, sodium salicylate, magnesium salicylate, salsalate, diflunisal, sodium thiosalicylate


  1. Leonards JR, et al. Gastrointestinal Blood Loss During Prolonged Aspirin Administration. N Engl J Med. Nov1973;289(19):1020-22.