How Iron interacts with indomethacin

Interaction type: Depletions

Interaction rating: Study Supported

This medication can cause irritation and bleeding in the digestive tract. Depending on the amount of blood lost, iron depletion may result. Supplementation with affected nutrient may be necessary. (1) (2)


  1. Gaginells TS. Drug-induced Malabsorption. Drug Therapy. Dec1975:88.
  2. View Abstract: Jallad NS, Cattan A, Weidler DJ. Efficacy of Misoprostol in Controlling Indomethacin Induced Fecal Blood Loss in Arthritic Patients. Int J Clin Pharmacol Ther Toxicol. Aug1993;31(8):376-81.