How Magnesium interacts with Aminoglycosides

Interaction type: Depletions

Interaction rating: Study Supported

These medications are reported to cause increased elimination of magnesium in the urine. Supplementation with the affected nutrient may be necessary. (1) (2)

These drugs include streptomycin, kanamycin, gentamicin, tobramycin, amakacin, netilmicin, neomycin, paromomycin


  1. View Abstract: Kes P, Reiner Z. Symptomatic Hypomagnesemia Associated with Gentamicin Therapy. Magnes Trace Elem. 1990;9(1):54-60.
  2. Jacobson ED, Faloon WW. Malabsorptive Effects of Neomycin in Commonly used Doses. A Am Med Assoc. 1961;175:187-90.