How Calcium interacts with digoxin

Interaction type: Depletions

Interaction rating: Proven

In an experiment with dogs, it was shown that digoxin can increase the amount of calcium eliminated from the body. Check with your healthcare professional to determine if supplementation with this nutrient is necessary. (1)


  1. Kupfer S, Kosovsky JD. Effects of cardiac glycosides on renal tubular transport of calcium, magnesium, inorganic phosphate and glucose in the dog. J Clin Investig. 1965;44:1143.