How Calcium interacts with Corticosteroid medications

Interaction type: Depletions

Interaction rating: Proven

Studies indicate that corticosteroids decrease the amount of calcium absorbed from your diet and increase the amount of calcium eliminated in the urine. Check with your healthcare professional to determine if supplementation with this nutrient is necessary. (1) (2)

These drugs include prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone, beclomethasone, flunisolide, fluticasone, fludrocortisone, mometasone


  1. View Abstract: Reid IR, et al. Evidence for Decreased Tubular Reabsorption of Calcium in Glucocorticoid-treated Asthmatics. Horm Res. 1987;27(4):200-04.
  2. View Abstract: Adachi JD, Ioannidis G. Calcium and vitamin D therapy in corticosteroid-induced bone loss: what is the evidence? Calcif Tissue Int. Oct1999;65(4):332-6.