How Calcium interacts with Potassium-sparing diuretics

Interaction type: Depletions

Interaction rating: Proven

It has been reported that these medications can cause increase the amount of calcium eliminated from the body. Check with your healthcare professional to determine if supplementation with this nutrient is necessary. (1)

These drugs include amiloride, triamterene, spironolactone


  1. Hanze S, et al. Studies of the Effect of the Diuretics Furosemide, Ethacrynic Acid and Triamterene on Renal Magnesium and Calcium Excretion. Klin Wochenschr. Mar1967;45(6):313-14.