How Selenium interacts with Corticosteroid medications

Interaction type: Depletions

Interaction rating: Study Supported

A study reported that high-doses of prednisolone in patients with rheumatoid arthritis may have decreased levels of selenium in their blood. Supplementation with the affected nutrient may be necessary. (1)

These drugs include prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone, beclomethasone, flunisolide, fluticasone, fludrocortisone, mometasone


  1. View Abstract: Peretz A, et al. Selenium Status in Relation to Clinical Variables and Corticosteroid Treatment in Rheumatoid Arthritis. J Rheumatol. Dec1987;14(6):1104-07.