How Selenium interacts with Oral contraceptives

Interaction type: Depletions

Interaction rating: Study Supported

A study reported that women taking oral contraceptives had decreased selenium levels in their blood compared to women not on oral contraceptive therapy. Supplementation with the affected nutrient may be necessary. (1)

These drugs include norethindrone, ethynodiol diacetate, norgestrel, norgestimate, ethinyl estradiol, drospirenone, desogestrel, levonorgestrel


  1. View Abstract: Heese HD, et al. Reference Concentrations of Serum Selenium and Manganese in Healthy Nulliparas. S Afr Med J. Feb1988;73(3):163-65.