How Sodium interacts with Loop diuretics

Interaction type: Depletions

Interaction rating: Proven

These medications have been reported to cause low levels of sodium in the body. Although this is expected, based on how these drugs work, supplementation with the affected nutrient may be necessary. (1)

These drugs include furosemide, bumetanide, ethacrynic acid, torsemide


  1. View Abstract: Andreasen F, Lauridsen IN, Hansen FA, et al. Dose Dependency of Furosemide-induced Sodium Excretion. J Pharmacol Exp Ther. Mar1989;248(3):1182-8.