How Zinc interacts with valproic acid

Interaction type: Depletions

Interaction rating: Study Supported

This medication has been reported to cause a significant decrease in zinc levels in the blood. Supplementation with the affected nutrient may be necessary. (1)


  1. View Abstract: Hurd RW, et al. Selenium, Zinc, and Copper Changes with Valproic Acid: Possible Relation to Drug Side Effects. Neurology. Oct1984;34(10):1393-95.