How Coenzyme Q10 (CO-Q10) interacts with Biguanides

Interaction type: Depletions

Interaction rating: Study Supported

Phenformin has been reported to decrease the formation of coenyzme-Q10 in the body. Supplementation with the affected nutrient may be necessary. (1)

These drugs include metformin


  1. View Abstract: Kishi T, et al. Bioenergetics in Clinical Medicine XI. Studies on Coenzyme Q and Diabetes Mellitus. J Med. 1976;7(3-4):307-21.