How Coenzyme Q10 (CO-Q10) interacts with Thiazide diuretics

Interaction type: Depletions

Interaction rating: Study Supported

These medications are reported decrease formation of coenzyme-Q10 in the body. Supplementation with the affected nutrient may be necessary. (1)

These drugs include hydrochlorothiazide, chlorothiazide, indapamide, metolazone, chlorthalidone, hydroflumethiazide, polythiazide, trichlormethiazide, benzthiazide, methyclothiazide, bendroflumethiazide

References

  1. View Abstract: Kishi H, et al. Bioenergetics in Clinical Medicine. III. Inhibition of Coenzyme Q10-enzymes by Clinically used Anti-hypertensive Drugs. Res Commun Chem Pathol Pharmacol. Nov1975;12(3):533-40.