How Vitamin B12 interacts with Potassium chloride, sustained / controlled release medications

Interaction type: Depletions

Interaction rating: Study Supported

These medications can change the amount of acid in the stomach, which may inhibit the absorption of vitamin B12 into the body. Supplementation with the affected nutrient may be necessary. (1)

These drugs include potassium chloride


  1. Palva IP, et al. Drug-induced Malabsorption of Vitamin B 12. IV. Malabsorption and Deficiency of B12 During Treatment with Slow-release Potassium Chloride. Acta Med Scand. Apr1972;191(4):355-57.