How Vitamin B6 interacts with levodopa

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Vitamin B6 may increase the breakdown of levodopa in the body, possibly altering the effectiveness of this medication. However, use of a drug product combining levodopa with carbidopa (Sinemet) is reported to avoid this potential problem. (1)


  1. View Abstract: Boshes B. Sinemet and the Treatment of Parkinsonism. Ann Intern Med. Mar1981;94(3):364-70.