How Vitamin C interacts with Corticosteroid medications

Interaction type: Depletions

Interaction rating: Study Supported

These medications have been reported to decrease the uptake of vitamin C into certain cells in the body. Supplementation with the affected nutrient may be necessary. (1)

These drugs include prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone, beclomethasone, flunisolide, fluticasone, fludrocortisone, mometasone


  1. View Abstract: Levine MA, Pollard HB. Hydrocortisone Inhibition of Ascorbic Acid Transport by Chromaffin Cells. FEBS Lett. 1983;158(1):134-38.