How Vitamin C interacts with Oral contraceptives

Interaction type: Depletions

Interaction rating: Study Supported

Studies report that use of these medications can decrease vitamin C levels in the blood. Supplementation with the affected nutrient may be necessary. (1) (2)

These drugs include norethindrone, ethynodiol diacetate, norgestrel, norgestimate, ethinyl estradiol, drospirenone, desogestrel, levonorgestrel


  1. View Abstract: Webb JL. Nutritional Effects of Oral Contraceptive Use: A Review. J Reprod Med. Oct1980;25(4):150-56.
  2. View Abstract: Nash AL, Cornish EJ, Hain R. Metabolic Effects of Oral Contraceptives Containing 30 Micrograms and 50 Micrograms of Oestrogen. Med J Aust. Sep1979;2(6):277-81.